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Nurse practitioner salary in the Charleston area

Start with Charleston-North Charleston, SC's BLS May 2025 employee wages: $126,750 mean annually and $127,780 median for nurse practitioners. These are wage estimates, not a promised offer or total compensation.

Charleston area wage snapshot

Nurse practitioner · SOC 29-1171 · Charleston-North Charleston, SC · May 2025
MeasureEstimate
Mean annual wage$126,750
Median annual wage$127,780
Employment estimate1,050
Wage relative standard error1.7%

Employee wages annualized at 2,080 hours. Not total compensation, guaranteed pay or a salary range. RSE measures estimate uncertainty, not your pay spread.

View official BLS wage data for this area

What the Charleston area row can tell you

BLS covers Charleston-North Charleston, SC as one metropolitan area. The published mean is $126,750, which is below the median of $127,780; BLS does not say why. The employment estimate of 1,050 counts employee jobs, not open positions. The wage relative standard error is 1.7%, which describes how uncertain the estimate is. It is not a pay percentile.

The South Carolina state mean for nurse practitioners is $124,170, so this metro mean is 2.1% above the state figure. The metro is part of the state estimate, so the two overlap.

Metro figures cover wage and salary employees only. Locum, 1099 and per diem pay can look very different, and benefits, call pay and bonuses are not included. Compare a written offer on hours, scope and benefits instead of reading these two wages as a salary range.

Source: BLS Occupational Employment and Wage Statistics, May 2025. How Saile salary pages work.

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How Charleston compares

Rank within this role group

Mean wage rank: 42 of 50; employment rank: 39 of 50. Rank = one plus metros with a larger estimate; ties share rank. This site’s group, not all US metros.

Versus highest-mean Los Angeles ($163,610): $36,860 (22.5%) below; versus lowest-mean Knoxville ($112,460): $14,290 (12.7%) above.

Dollar gap = metro mean minus comparator mean; percent = difference divided by comparator, times 100. Absolute gaps shown.

National comparison

BLS OEWS national mean: $137,300; Charleston is $10,550 (7.7%) below it, using the same gap formulas.

Same-state context

This is the only metro in this role group mapped to South Carolina; see the South Carolina state pay page.

South Carolina mean: $124,170; employment: 5,670. Metro share = 1,050 divided by 5,670, multiplied by 100 = 18.5%. Overlapping estimates; multi-state ratios are not resident shares.

Same metro, other roles

Family medicine physician mean in Charleston: $256,810; Internal medicine physician mean in Charleston: $340,400; Physician assistant mean in Charleston: $123,350

What to check before using this number

Read $126,750 beside $127,780: the mean is $1,030 (0.8%) below the median, not evidence of why wages differ.

The group median wage RSE is 1.8% versus 1.7% here; lower RSE means different relative uncertainty, not a negotiation band.

Employment of 1,050 is below the 1,790 group median; these are employee jobs, not vacancies.

Mean–median = mean minus median. Group median = middle sorted value (average of middle pair); unavailable RSE excluded.

Licensing in South Carolina: physician state licensing guidance; NP licensing guide. Check the relevant board and facility for your role.

Source: BLS OEWS May 2025 metro/state rows; wages, not total compensation.

Nurse practitioner salary questions in the Charleston area

What is the average nurse practitioner salary in the Charleston area?

BLS May 2025 estimates a mean annual employee wage of $126,750 and a median of $127,780 for nurse practitioners in Charleston-North Charleston, SC. The mean is the average; the median is the midpoint. These are employee wages, not total compensation, a guaranteed offer or a salary range.

What is the hourly pay equivalent in the Charleston area?

Dividing the annual wage estimates by 2,080 hours gives about $60.94 per hour for the mean and $61.43 for the median, rounded to cents. This is an arithmetic equivalent, not a quoted locums, per-diem or telemedicine rate.

How many nurse practitioners work in the Charleston area?

BLS estimates 1,050 nurse practitioners employed as wage and salary employees in Charleston-North Charleston, SC. This counts employee jobs, not open positions or current vacancies.

How does the Charleston area pay compare with South Carolina?

The South Carolina state mean for nurse practitioners is $124,170, so this metro mean is 2.1% above the state figure. The metro is part of the state estimate, so the two overlap.

How reliable is this metro estimate?

The wage relative standard error for this row is 1.7%. RSE describes how uncertain the estimate is. It is not a pay percentile or a negotiating band.

Where does Charleston rank for nurse practitioner mean wages?

Charleston ranks 42 of 50 by mean wage and 39 of 50 by employment in this site's role group. Rank = one plus metros with larger estimates; ties share rank. This is not every US metro.

Which other South Carolina metros can I compare with Charleston?

Charleston is the only metro in this site's role group mapped to South Carolina. The linked state page reports a $124,170 mean; a single listed metro does not mean the state has no other labor markets.

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