Oklahoma DEA registration and controlled substance licensing

Facts

DEA listing

DEA lists Oklahoma under: Second CS License Requirement

Note

DEA's page titles this column 'Second CS License Requirement', which DEA's page presents as a state controlled substance license in addition to the medical license. Confirm the exact requirement with the Oklahoma licensing board before prescribing.

DEA: Medical State Licensure and/or Controlled Substance Licensure

Moving to or adding Oklahoma

• Get the Oklahoma license first.
• Then apply for or update the DEA registration for Oklahoma. Per the DEA Registration Q&A, a separate DEA registration is needed in each state where you practice and dispense controlled substances.
• DEA registration page

NPs and PAs

DEA treats NPs and PAs as mid-level practitioners. Authority comes from state law, so check the Oklahoma board.

Decision checklist for Oklahoma

• Describe the proposed professional practice location and dispensing work in Oklahoma.
• Compare that location with the principal-place registration rule in 21 CFR 1301.12.
• Resolve the state authorization question independently of the federal registration application.

The DEA Registration Q&A separately addresses different-state practices; confirm individual state authority.

Find your state board (FSMB directory)

Neighbors

2 of the 6 bordering states are listed with a second-CS-license flag: Missouri, New Mexico.

• Arkansas — one-license flag.
• Colorado — one-license flag.
• Kansas — one-license flag.
• Missouri — second-CS-license flag.
• New Mexico — second-CS-license flag.
• Texas — one-license flag.

Count named qualifying land/river neighbors; exclude water-only and corner-only contacts. Neighbor status grants no practice authority.

In this state, in context

BLS OEWS May 2025 annual mean employee wages — physicians, all other: $248,930; nurse practitioners: $134,200; physician assistants: $138,700. “Physicians, all other” is a broad category, not all physicians or a specialty average. These are employee wage estimates, not total compensation or contract rates.

Oklahoma physicians, all other pay · Oklahoma nurse practitioners pay · Oklahoma physician assistants pay · Oklahoma nurse anesthetists pay

Sources

• DEA: Medical State Licensure and/or Controlled Substance Licensure
• DEA Diversion Control Division: Registration Q&A
• 21 CFR 1301.12 (Cornell LII)
• DEA: Registration

General information, not legal or insurance advice. Confirm details with the state board, DEA, or the carrier.