Colorado DEA registration and controlled substance licensing

DEA lists Colorado under "One License Requirement" on its page "Medical State Licensure and/or Controlled Substance Licensure". A DEA registration depends on authority to dispense controlled substances under Colorado law.

Facts

DEA listing
DEA lists Colorado under: One License Requirement
Note
DEA's page titles this column 'One License Requirement'.

DEA: Medical State Licensure and/or Controlled Substance Licensure

Moving to or adding Colorado

  • Get the Colorado license first.
  • Then apply for or update the DEA registration for Colorado. Per the DEA Registration Q&A, a separate DEA registration is needed in each state where you practice and dispense controlled substances.
  • DEA registration page

NPs and PAs

DEA treats NPs and PAs as mid-level practitioners. Authority comes from state law, so check the Colorado board.

Neighbors

4 of the 6 bordering states are listed with a second-CS-license flag: New Mexico, Oklahoma, Utah, Wyoming.

The count is the number of named qualifying neighbors out of all listed land/river neighbors. Open-water-only and point-only contacts are excluded; a neighboring status does not grant practice authority here.

In this state, in context

BLS OEWS May 2025 annual mean employee wages — physicians, all other: $298,570; nurse practitioners: $132,540; physician assistants: $139,580. The physician row is the broad “physicians, all other” category, not an average for all physicians or a particular specialty. These are employee wage estimates, not total compensation or contract rates.

Colorado physicians, all other pay · Colorado nurse practitioners pay · Colorado physician assistants pay

Decision checklist for Colorado

  • Identify each principal place of business or professional practice in Colorado where controlled substances are dispensed.
  • Read 21 CFR 1301.12 for separate registration at each such place at one general physical location.
  • Confirm state authorization separately; a DEA registration depends on authority under state law.

The DEA Registration Q&A separately explains registration for practices in different states. The state listing is a flag to verify, not a complete description of an individual clinician’s authority.

Find your state board (FSMB directory)

Sources

General information, not legal or insurance advice. Confirm details with the state board, DEA, or the carrier.

Frequently asked questions

How does DEA list Colorado?

DEA lists Colorado under "One License Requirement" on its page "Medical State Licensure and/or Controlled Substance Licensure". DEA's page titles this column 'One License Requirement'.

Do I need a separate DEA registration for Colorado?

According to the DEA Registration Q&A, a practitioner with practices in two states needs a separate DEA registration in each state, because controlled substance privileges and limits are determined by that state.

Can NPs and PAs prescribe controlled substances in Colorado?

DEA treats NPs and PAs as mid-level practitioners, and their authority comes from state law. Check the Colorado board.

How many neighbors of Colorado are listed with a second-CS-license flag?

4 of the 6 bordering states are listed with a second-CS-license flag: New Mexico, Oklahoma, Utah, Wyoming.

Can the Colorado wage links establish permission to practice?

No. The linked BLS state wage estimates describe employee wages, not licensing, compact privileges or prescribing authority. Confirm the Colorado board’s requirements separately.